LPL and hyperlipidemia: Hyperlipidemia is associated with thrombosis and other severe complications, but no standard recommendations are provided for screening or monitoring of hyperlipidemia in the treatment of L-Asp.6, 9, 10, 11, 12, 13, 14While the elevated TG levels in pediatric ALL patients are generally transient and rarely necessitate the suspension of therapy, significant increases in TG levels are thought to be attributed partially to genetic predisposition,15as evidenced by the child in this case who exhibited abnormal TG and LPL gene mutation during L-Asp treatment.