Higher IL-12p70 levels were associated with slower cognitive decline at higher amyloid-β levels (Leinonen et al., 2011), and high IL-12p70 was associated with reduced tau protein and neurodegeneration in participants with high amyloid-β (Said et al., 2022), a conclusion highlighting the possible association between iNPH and neurodegenerative disease. The gene discussed is MAPT; the disease is neurodegenerative disease.