In Model III (adjusted for family PIR, BMI, education level, drinking, smoking, cotinine, ALT, AST, BUN, GGT, LDH, diabetes, hypertension, and ACR in addition to Model II), the Q3 and Q4 quartiles groups had a higher risk of hyperuricemia than Q1 (Q3: OR: 1.28, 95%CI=1.03–1.59; Q4: OR: 1.49, 95%CI=1.21–1.84; P for trend <0.05). The gene discussed is GPT; the disease is diabetes mellitus.