In Model III (adjusted for family PIR, education level, BMI, drinking, smoking, cotinine, ALT, AST, BUN, GGT, LDH, diabetes and ACR in addition to Model II), the Q3 and Q4 quartiles had a higher risk of hyperuricemia (Q3: OR:1.20, 95%CI=1.01–1.42; Q4: OR: 1.28, 95%CI=1.08–1.52). The gene discussed is GPT; the disease is diabetes mellitus.