After adjusting for family PIR, education level, BMI, drinking, smoking, cotinine, ALT, AST, BUN, GGT, LDH, hypertension, and ACR in addition to Model II (P for trend <0.05), the risk of hyperuricemia increased by 40% (OR:1.40, 95%CI=1.21–1.62) in Q4 compared to Q1. This evidence concerns the gene GPT and Hypertension.