Coexistence of CD10 and EGFR overexpression was found in 2 out of 8 patients (25%) and was associated with age, tumor size and with the aggressive histologic type of phyllodes tumors (sarcoma), data are shown in Table 5, in contrast, in the group of tumors underestimating CD10 and EGFR proteins, patients had benign phyllodes tumors (100%). The gene discussed is EGFR; the disease is sarcoma.