Results: The Malat1expression was inversely correlated with stroke severity (r=-0.25, P=0.043).Stepwise regression analysis showed a significant positive relationship betweenVitD level and Malat1 expression (Beta=0.28, P=0.02), and also showed anon-significant negative relationship between IL-1β and stroke severity. The gene discussed is MALAT1; the disease is stroke disorder.