While the photothermal technique for eliminatingtumor cells proves to be highly efficient, the complexity of laserirradiation in in vivo applications is highly impractical.34,35 T. Anajafi et al. engineered redox-sensitive polymersomes for targetedcurcumin and DOX delivery to the nucleus in pancreatic cancer, enhancingdrug accumulation at tumor sites.36 Employinga matrix metalloproteinase-7 (MMP-7) peptide linker, the researchershave activated nuclear localization signal (NLS) peptides selectivelyin high MMP-7 concentrations within tumors. This evidence concerns the gene MMP7 and familial pancreatic carcinoma.