MAP1LC3A and cancer: In a recent study, downregulation of LC3 gene bydelivering siLC3significantly reduced cell viability and blocked the main cell mechanisms;proliferation, invasion, migration, and resistance to apoptosis inthe metastatic MDA-MB-231 cell line, which represents a simulationof TNBC.58 A naturally occurring kava chalconecalled flavokawain B (FKB) has a potent anticancer effect on a numberof cancer types that also activate autophagy.