UNC51-likekinase 1 (ULK1) is one of the ATGs that participatesin the formation of autophagosomes,191 andwhen it is inhibited, cancer cells exhibit an effective reductionof autophagy and an increase in apoptosis.192,193 For instance, a reduction in the proliferation, migration, invasion,and autophagy of pancreatic cancer has been seen by inhibiting ULK1via miR-372.194 Recent research found thatmiR-373 inhibited ULK1, which in turn promoted apoptosis in cholangiocarcinomacells via suppressing autophagy. This evidence concerns the gene ULK1 and cancer.