GAPDH and cancer: They are biocompatible andbiodegradable, and they can recognize and target cancers.269 They can readily be coated with hydrophilicpolymers, like PEG, to lengthen the in vivo circulation period.270 For instance, one study used PEGylated liposomesto deliver glyceraldehyde-3-phosphate dehydrogenase (GAPDH) siRNAand PTX simultaneously.