Similarly, it has been shown that IL-10–/– mice have lower bacterial burden at the site of infection during S. aureus skin infection because of enhanced effector γδ+ T cell migration into the skin abscess and increased IL-17 and IFN-γ secretion by γδ+ and CD4+ T cells, respectively, compared with WT mice (29). The gene discussed is IFNG; the disease is Cutaneous abscess.