FGL1 and neoplasm: In the liver orthotopic tumor of Hepa1-6 in situ inoculation, the morphology of liver showed that pretreatment with the anti-FGL1 mAb inhibited orthotopic tumor growth (Figure 5E), which was further verified by the significantly decreased tumor diameter in the livers of the anti-FGL1 mAb–treated mice (Figure 5F).