DHODH and cancer: DHODH inhibitors have shown robust preclinical anticancer activity across diverse cancer types (Shukla et al., 2017; Christian et al., 2019; Sykes et al., 2016; Wang et al., 2019; Koundinya et al., 2018; Santana-Codina et al., 2018; Brown et al., 2017; Mathur et al., 2017; Li et al., 2019a; Bajzikova et al., 2019) and have recently entered clinical trials for multiple hematological cancers (NCT04609826 and NCT02509052).