USP5 and hepatocellular carcinoma: For instance, it participates in USP5‐Beclin1 axis activation in non‐small cell lung cancer, reducing p53‐dependent senescence.[17] Alternatively, it stabilizes SLUG to promote epithelial‐mesenchymal transition in hepatocellular carcinoma.[18] However, USP5 has not been explicitly reported in GISTs.