Next, we used immunohistochemical staining to investigate PKC-δ expression in kidney biopsies from patients with CKD, including IgA nephropathy, focal segmental glomerulosclerosis (FSGS), diabetic kidney disease (DKD), and class V Lupus nephritis (Fig. 1F). The gene discussed is PRKCD; the disease is focal segmental glomerulosclerosis.