On comparing the PCSK9 level in the two sepsis groups according to different organ dysfunction developed, children with sepsis or severe sepsis who developed any organ dysfunction had higher PCSK9 when compared to children with sepsis and severe sepsis who did not suffer that organ dysfunction, as p ≤ 0.001 in all, except for renal and hepatic dysfunction, where p = 0.004 and 0.008 respectively. The gene discussed is PCSK9; the disease is Sepsis.