Among them, COL5A1 and LUM were significantly increased in the HF dataset (P < 0.05, Figure 8E, 8F), but TGFB2, FMOD, ASPN, and COL14A1 were significantly decreased in the HF dataset (P < 0.05, Figure 8G–8J). The gene discussed is ASPN; the disease is hydrops fetalis.