As shown in Supplementary Fig. 5A, B, ATP6V0A1 protein levels were significantly higher in 6 human CRC cell lines (CACO2, HCT-8, HCT-116, HT-29, RKO, and SW620) than in normal human colon epithelial NCM460 cells. The gene discussed is ATP6V0A1; the disease is colorectal carcinoma.