LYVE1 and liver disorder: This evidence could support the notion that h-NG2/BMMSCs have superior therapeutic effects to parental h-BMMSCs on liver diseases. Interestingly, when analyzed by performing IF staining (red) of Lyve-1 expression in the host liver, we obtained evidence similar to that collected for animal cells regarding sinusoidal repair in DEN-induced livers [Fig. 6F(a-d)]. We detected ∼ 5 ± 3.06 Lyve-1+ cells/per quarter area (b) in DEN mice, which was significantly lower than that in naive livers (a, ∼ 11.58 ± 3.72/quarter area/boxes; e, #p < 0.05).