RNPC3 and systemic lupus erythematosus: While the monogenic lupus group can also exhibit various positive autoantibodies, the classic SLE group is more likely to present with lupus-specific antibodies, such as antinuclear antibodies, anti-double strand-DNA antibodies, anti-Smith antibodies, anti-ribonuclear protein (RNP) antibodies, anti-Sjogren's syndrome antigen A antibodies, anti-ribosomal RNP antibodies, anti-Ro-52 antibodies, anti-complement antibodies, anti-nucleosome antibodies, and lupus anticoagulants.