On the other hand, statins were reported to develop the ubiquitin‐proteasome system in muscle, which is now thought to be a possible mechanism of statin‐associated myopathies.[40] Our results supported that PAQR9 associated proteasome system was activated in the liver, however, no significant changes in STUB1 were observed, revealing a different regulatory pattern of statins in liver. The gene discussed is PAQR9; the disease is myopathy.