To explore whether NDRG1 is engaged in the DDR pathway and thereby regulates cervical cancer radiosensitivity, we examined the role of NDRG1 in homologous recombination (HR) and non-homologous end joining (NHEJ) by performing I-Secl-based HR and NHEJ reporter assays, respectively. This evidence concerns the gene NDRG1 and cervical cancer.