BCR and acute lymphoblastic leukemia: Our data indeed suggest slightly more frequent breaks in the 5’ portion of ABL1 and downstream of intron 13 of BCR (more typical for CML) in CML-like leukemias than in typical ALL (data not shown), but the differences are relatively small and do not reach statistical significance, possibly due to the limited number of patients for this analysis (99 typical ALL vs. 53 CML-like leukemias).