MELK and neoplasm: To this end, we conducted a holistic view of the expression characteristics of MELK in tumors in different organs from the TCGA database (Figure S1A-B), and analysis of the TCGA-LIHC cohort (Fig. 1A), ICGC cohort (Fig. 1B) and GSE14520 cohort (Fig. 1C) revealed that the expression of MELK in tumor tissues was significantly increased compared to that in normal tissues.