Two patients had paired breast, CM and lymph node metastasis samples: patient 1 exhibited one shared mutation in TP53 between the primary tumor and CM, one shared copy number amplification in FGFR2 between the primary tumor and lymph node, no shared alterations between CM and lymph node, and two specific alterations in the lymph node. The gene discussed is FGFR2; the disease is metastatic malignant neoplasm in the lymph nodes.