The major signaling pathways (KEGG) related to these genes included the PI3K-Akt signaling pathway (hsa04151, 73 genes), pathways in cancer (hsa05200, 66 genes), JAK-STAT signaling pathway (hsa04630, 62 genes), cell cycle (hsa04110, 59 genes), cytokine-cytokine receptor interaction (hsa04060, 59 genes), MAPK signaling pathway (hsa04010, 44 genes), Ras signaling pathway (hsa04014, 41 genes), Rap1 signaling pathway (hsa04015, 36 genes), and calcium signaling pathway (hsa04020, 27 genes). The gene discussed is SOAT1; the disease is cancer.