Among the altered genes related to the cell cycle, MYC, Cyclin A2 (CCNA2), Cyclin E2 (CCNE2), Cyclin D2 (CCND2), CD133 (PROM1) and Cyclin-dependent kinase (CDK1) were more highly expressed in the HSCs from AML condition than in those of the Healthy condition (Fig. 4). This evidence concerns the gene CCND2 and acute myeloid leukemia.