In addition, we evaluated the effect of BNIP3 on cell competition through treating the cell competition xenograft models in vivo with BNIP3 inhibitor olomoucine (Fig. 4M) and found that the specific inhibition of BNIP3 effectively suppressed tumor growth (Fig. 4N, O; Supplemental Fig. S5J). The gene discussed is BNIP3; the disease is neoplasm.