In addition, TNBCs had significantly higher proportions of 14_ProliMac compared to HR + /HER2+ positive breast cancers, with the reverse trend for 2_C3Macs, which were higher in HR + /HER2+ positive breast cancers compared to TNBCs (Moderated two-sided T-test via Propeller with FDR correction for multiple testing, q = 0.0594 and q = 0.0761 respectively; Supplementary Fig. 7). This evidence concerns the gene ERBB2 and breast cancer.