CGAS and viral infectious disease: Given that it has been reported that in Calu-3 cells infected by SARS-CoV-2 there is a strong cGAS/STING induction (up to 98 folds) as consequence to viral infection (Mösbauer et al., 2021; Zhou et al., 2021), the higher potency of SARS-CoV-2 inhibition observed in Calu-3 confirmed the mode of action of the compounds.