The cyclic GMP-AMP synthase (cGAS) - Stimulator of Interferon Genes (STING) pathway is a major line of defense against viral and bacterial infections and tumor onset (Barber, 2015; Burdette et al., 2011; Cai et al., 2020; Li et al., 2017, 2020; Paulis and Tramontano, 2023; Woo et al., 2014a). The gene discussed is CGAS; the disease is bacterial infectious disease.