Examples of such shared TFs between NEPC and SCLC subtypes included ASCL1, HOXB5, ETS2, ELF3, XBP1, and PROX1 (ASCL1 subtype), and NEUROD1, HES6, TCF4, NFIA, and JARID2 (NEUROD1 subtype). The gene discussed is XBP1; the disease is small cell lung carcinoma.