PSMB8 and central nervous system cancer: According to previous research, it has been confirmed that the dysregulation of lncRNA plays a crucial role in the pathogenesis, progression, and malignancy of glioma [28, 29] For example, a lncRNA called PSMB8-AS1 can enhance the proliferation and migration of glioma cells, as well as inhibit apoptosis, by competitively binding with miR-382-3p and increasing the expression of branched-chain amino acid transferase 1 (BCAT1) [30].