Meanwhile, miR-1299 was found to be a negative regulator of ST AT3 in colon cancer [61], which targeted deletion of miR-139-5p, activating STAT3 signaling and promoting progression of colorectal cancer [62], and miR-125b inhibited cell proliferation by targeting STAT3 [63]. The gene discussed is STAT3; the disease is malignant colon neoplasm.