HNRNPA2B1 is an RNA-binding protein involved in many post-transcriptional RNA regulation processes [56, 57] that has been shown to be differentially expressed upon glucose exposure in human EndoC-βH1 cells [58] and to regulate intracellular and secreted insulin content in mouse insulinoma MIN6 cells [59]. This evidence concerns the gene HNRNPA2B1 and pancreatic insulinoma.