The same author group investigated the predictive value of ∆ADC combined with the quantitative DCE-feature percentage change in functional tumor volume (∆FTV%) and found a small but significant added value of ∆ADCmean(%) within HER2-positive and HR-positive patients but also did not take inter-reader variance nor MRI field strength into account [22]. The gene discussed is ERBB2; the disease is neoplasm.