GLI proteins potentially contribute to pulmonary fibrosis development through various mechanisms, including controlling the expression of proliferative and antiapoptotic genes, regulating collagen production, inducing Snail expression to promote epithelial‐to‐mesenchymal transition, and modulating the transcriptional activity of the alpha‐SMA gene to promote fibroblast‐to‐myofibroblast differentiation.18, 19. Here, GLI1 is linked to pulmonary fibrosis.