Three of the fusion partners among adults with CRC harboring an NTRK gene fusion tumor have been commonly reported in the literature, including TPM3::NTRK1 [8, 17, 20, 24, 27–30], TPR::NTRK1 [20, 24, 25, 29, 30], and LMNA::NTRK1 [8, 20, 24, 25, 27, 28, 30, 31]. The gene discussed is TPM3; the disease is colorectal carcinoma.