MSH6 and colorectal carcinoma: Of the two other patients with CRC, one had a tumor harboring a GABRG1::NTRK3 fusion, and the other had a tumor harboring the NTRK2 gene with two different fusion partners identified from one sample – FXN and LPPR1. Five of these eight patients with CRC had tumors tested for MSI with four mismatch repair proteins (MLH1, MSH2, MSH6, and PMS2).