IRF2BP2 and colorectal carcinoma: The other NTRK gene fusions that we identified in our adult CRC cohort were IRF2BP2::NTRK1 (which has been reported previously among adult tumors) [2], GABRG1::NTRK3, and a fusion of the NTRK2 gene with two different fusion partners – FXM and LPPR1 – identified from a single tissue sample.