have measured the concentration of CRP on two consecutive days in 90 FN episodes experienced by 47 children, finding that although the concentration of CRP in patients with bacteremia is significantly higher than that in non‐bacteremia patients, the diagnostic accuracy is unsatisfied,27 which is consistent with the conclusion of Doerflinge and de Araujo demonstrating CRP shows a low value for bacteremia diagnosis.7, 28. This evidence concerns the gene CRP and bacterial infectious disease with sepsis.