In this study, we advanced the observation time to 12 h, finding that unlike IL‐6 was consistently at high levels in the IAI group, IL‐6 reduced obviously at the early stage of anti‐infection (12 h) in the IAE group, which is similar to the study reported by Delgado et al., revealing that IL‐6 reached to a peak value at the onset of fever, followed by a decrease on the second day (12–24 h).15 Here, IL6 is linked to infection.