In the current study, SLE rats demonstrated significantly higher expression levels of circ-CDC27 (circ-0044235), circ-Med14 (circ-0140271), rno-miR-146a-5p, and TRAF6, with significantly lower expression levels of circ-TubD1 (circ-0044897). This evidence concerns the gene MED14 and systemic lupus erythematosus.