NFKB1 and Sepsis: NFκB is a pivotal transcription factor that predicts sepsis severity and mortality and induces a variety of downstream proinflammatory effectors (Barnes and Karin, 1997; Böhrer et al., 1997; Arnalich et al., 2000; Abraham, 2003; Basak and Akashi-Takamura, 2024).