In our meta-analysis, the pooled sensitivity of 68Ga-PSMA-11 PET in the initial lymph node staging of prostate cancer was found to be 0.73 (95% CI: 0.51–0.91), while mpMRI demonstrated a sensitivity of 0.49 (95% CI: 0.30–0.68). This evidence concerns the gene FOLH1 and prostate cancer.