ALB and Crouzon syndrome-acanthosis nigricans syndrome: CAN: cardiac autonomic neuropathy; HbA1C: glycated hemoglobin; eGFR: estimated glomerular filtration rate; UACR: urinary albumin‐to‐creatinine ratio; TC: total cholesterol; LDL: low-density lipoproteins; HDL: high-density lipoproteins; TG: triglycerides.