MTSS identified independent risk factors for poor survival after transplant (pretransplantation thrombocytopenia, leukocytosis, older age, poor performance according to Karnofsky performance status, a non-CALR/MPL driver mutation genotype, ASXL1-mutation and transplantation from an HLA-mismatched unrelated donor). This evidence concerns the gene ASXL1 and Increased total leukocyte count.