GPHN and Anxiety: It was shown that the amplitude of mIPSCs was increased in the LV‐GphnC212A group compared with that of LV‐eGFP group, with no change in the frequency (Figure 4K–M), indicating that sGABAAR γ2 expression modulated by inhibition of SNO‐gephyrin at Cys212 is essential for improving anxiety‐like behaviors.