Compared with the healthy people, the expression levels of GPAT3 was significantly reduced (Fig. 9J), while the expression level of FOSB, RGCC, and RNF43 showed no significant change (Fig. 9I, K, L) in patients with hepatitis B; the expression levels of RNF43 was significantly increased (Fig. 10D), while the expression level of FOSB, RGCC, and GPAT3 showed no significant change (Fig. 9A, B, C) in patients with hepatitis C; the expression level of RGCC was significantly reduced (Fig. 9G), while the expression level of RNF43 was significant increased (Fig. 9H) in the AIH patients. The gene discussed is RNF43; the disease is autoimmune hepatitis.