The CD70/CD27 signaling is found activated in acute or chronic myeloid leukemia stem cells and contributes to the stemness formation of these cells by activating the WNT pathway.374–376 CD34+/CD38− is also identified as a marker for myeloid leukemia stem cells and has been widely used.2 Compared to myeloid leukemia, CSC markers for lymphoblastic leukemia are hardly reported. This evidence concerns the gene CD38 and myeloid leukemia.