PROM1 and hepatocellular carcinoma: For instance, while CD133+, CD166+CD44+, and CD24+CD44+ phenotypes of human colorectal cells do not correlate with stem cell properties, these 3 sets of markers are reported as CSC-specific in colorectal cancer.378 Plus, ALDH1 alone does not correlate with stem cell-like features in hepatocellular cancer cells,379 but CD133+ALDH+ cells are significantly more tumorigenic than their CD133−ALDH+ or CD133−ALDH− counterparts,380 suggesting that combined use of CD133 and ALDH can better distinguish hepatocellular CSCs.