CD27 and chronic myelogenous leukemia, BCR-ABL1 positive: The CD70/CD27 signaling is found activated in acute or chronic myeloid leukemia stem cells and contributes to the stemness formation of these cells by activating the WNT pathway.374–376 CD34+/CD38− is also identified as a marker for myeloid leukemia stem cells and has been widely used.2 Compared to myeloid leukemia, CSC markers for lymphoblastic leukemia are hardly reported.