Next, we investigated the association of LSCs and fatty acid metabolism-related clusters with classical clinical features of AML in the TCGA-LAML cohort, LSCs and fatty acid metabolism related-clusters, survival status, overall survival, age, sex, FAB typing, WAB number, cytogenetic risk, CD34, proportion of progenitor cells, proportion of precursor cells in bone marrow, FLT3 gene mutation, NPM1 mutation, and expression profile of each gene were used as annotations (Fig. 1M). The gene discussed is NPM1; the disease is acute myeloid leukemia.