In recent years, Lathyrol has been found to act through various pathways, such as the inhibition of the NF-κB pathway and related proteins in cancer tissues, promote the apoptosis of RCC cells and inhibit the proliferation and invasion of Renca cells to a certain extent by inhibiting the expression and activation of proteins in the TGF-β/Smad pathway. This evidence concerns the gene NFKB1 and cancer.