We next extended our analysis from the 5 patients with at least 1 HLA-DRB1*11 allele to all 12 patients with ARLA with available TCR sequences and performed GLIPH2 on TCR-β sequences derived from bulk sorted PD-1hiCD4+ T cells from all patients with ARLA as well as on published data from patients with RA or JIA (input: 20,486, 25,095, and 8,698 sequences from ARLA, JIA, and RA respectively (24, 29)) and visualized the results using network analysis. The gene discussed is HLA-DRB1; the disease is rheumatoid arthritis.