ACE2 and COVID-19: Nicotine (NC) is known to be a highly addictive ingredient of tobacco that diminishes autonomy over smoking and affects, possibly exacerbates, the severity of coronavirus disease 2019 (COVID‐19) by modulating the target nicotinic acetylcholine receptors (nAChRs) and relevant molecular systems (e.g., angiotensin‐converting enzyme 2‐related system).1, 2, 3