STIM1 and trigeminal neuralgia: Considering the role of STIM1 in regulating the SOCE pathway and the release of inflammatory cytokines in T lymphocytes, as well as its central position in the pathogenesis of trigeminal neuralgia, we believe that STIM1 is a novel target for the treatment of trigeminal Although drug development for STIM1 is still in the early stages, according to our research, further drug screening and efficacy evaluation targeting STIM1 could be carried out, providing new strategies for the treatment of trigeminal neuralgia.