Currently, a considerable number of genes have been linked to 46, XY DSD, such as, SRY, TSPYL1, WNT4, WT1, WWOX, ZFPM2, AKR1C2, AKR1C4, AMH, CYB5A, CYP11A1, CYP17A1, HSD17B3, HSD3B2, LHCGR, POR, and AR [7]. Here, CYB5A is linked to disorder of sexual differentiation.