Currently, a considerable number of genes have been linked to 46, XY DSD, such as, SRY, TSPYL1, WNT4, WT1, WWOX, ZFPM2, AKR1C2, AKR1C4, AMH, CYB5A, CYP11A1, CYP17A1, HSD17B3, HSD3B2, LHCGR, POR, and AR [7]. This evidence concerns the gene TSPYL1 and disorder of sexual differentiation.