EREG and colorectal carcinoma: Furthermore, we examined the associations of ARC with CMS and CSC index (included mRNAsi and EREG mRNAsi index) in CRC patients (Figure 3A); the results showed that cluster I showed higher mRNAsi index than cluster II, but there was no significant difference regarding EREG mRNAsi index between cluster I and cluster II (Figure 3B).